Chromatography and Mass Spectrometer Laboratory
High-Performance Liquid Chromatography (HPLC)
The 1260 Infinity II LC System is a robust high performance liquid chromatography instrument that offers the widest choice of modules for analytical HPLC. It delivers the performance, reliability, and robustness you need for highest confidence in your daily results.
Features:
- Compatible with conventional and ultrahigh performance LC: 1260 Infinity II Quaternary Pump and 1260 Infinity Binary Pump operate up to 600 bar, a perfect match for our InfinityLab Poroshell 120 columns
- Analytical and semipreparative purifications: wide flow range of the 1260 Infinity II Quaternary Pump (up to 10 mL/min) perfectly supports standard and semipreparative applications
- Fast and precise gradients: 1260 Infinity II Binary Pump is the perfect choice for fast and precise gradients using LC/MS, as well as UV-only systems
- Ultralow carryover: multiwash capability of the 1260 Infinity II Multisampler cleans all relevant injection parts between runs, flushing the injection needle outside with three solvents using seat backflush procedures to reduce carryover to less than 10 ppm
- Reduced cycle times: with the unique Agilent dual-needle design, run samples alternately through one or the other injection path. Can reduce cycle times to mere seconds, virtually eliminating conventional wait times – whether for large volume loadings or flushing procedures
- Efficient sample handling and logistics: using shallow well-plate drawers, 1260 Infinity II Multisampler takes a maximum load of 16 microtiter plates and up to 6,144 samples – the most of any single system
- Efficient column handling and temperature control: 1260 Infinity II Multicolumn Thermostat holds up to four columns with direct access to each column through a Quick-Change switching valve, delivering flexibility and eliminating the need to disconnect and reconnect columns
- Higher quality data: 1260 Infinity II Diode Array Detector HS delivers lower detection limits and higher data quality for more confidence
- Efficient control, acquisition, and reporting: Agilent instrument control framework (ICF) enables smooth control of Agilent LC instrumentation through third-party chromatography data systems
Quadrupole Time-of-Flight Mass Spectrometry (QTOF/LC-MS)
Raise your analysis to a new level with the Agilent 6530 Q-TOF mass spectrometer. Full MS spectra followed by MS/MS or All Ions acquisition make this instrument suitable for applications in the pharmaceutical industry as well as life sciences and governmental agencies. Accurate mass spectrometry enables you to gain more confidence in your analysis compared to unit resolution instrumentation.
The 6530 Q-TOF LC/MS delivers the power of accurate-mass mass spectrometry, so you can be fully confident of your data. All software workflows from our high-end and mid-range instruments are fully compatible with the 6530, giving you the most powerful access to your data and research possible. The demonstrated robustness of the 6530 will keep your lab up to speed.
Features:
- Mass accuracy within 2 ppm gives you complete confidence in your analysis.
- Powerful Agilent Jet Stream source enables you to uncover low level components.
- Wide in-spectrum dynamic range facilitates simultaneous measurement of minor components in the presence of intense background interferences.
- The latest developments in Agilent Infinity II UHPLC, 2D-LC, SFC, and even GC-APCI chromatographic interfaces give you blazing fast acquisition speed.
- Powerful MassHunter software provides the latest software capabilities for profiling, characterizing, identifying, and quantifying compounds in complex mixtures via high-definition MS and MS/MS.
- Untargeted screening and quantitation using Agilent’s All Ions MS/MS technique.
Gas Chromatography (GC)
The Agilent 5977B GC/MSD is the latest in the series of most trusted single quadrupole GC/MS instruments. It is ideal for labs that focus on applications such as environmental, chemical, petrochemical, food, forensic, pharmaceutical, and material testing.
Building on a long track record of innovation, the High Efficiency Source (HES) and Inert Plus Extractor EI source maximize the number of ions that are created and transferred out of the source body and into the quadrupole analyzer. This novel mass selective detector improves sample throughput, analytical performance, and business outcomes, making the 5977B the most popular single quadrupole GC/MS for routine, robust, and reliable use.
Features:
- Improve sensitivity (10x greater) with detection limits as low as 1.5 fg IDL, bringing yesterday’s triple quadrupole limits of detection into today’s single quadrupole laboratory
- Reduce time spent on sample prep and maintenance, while meeting your current sensitivity requirements, with just 1/10 of the original sample volume
- Minimize operating and shipping costs by storing, prepping, and disposing of 10x less material
- Benefit from eco-friendly features, such as Sleep/Wake modes, and conserve electricity and other resources like carrier gas
- Greatly reduce or even eliminate the need for manual source cleaning with the JetClean self-cleaning ion source
- The built-in intelligence of the 8890 GC drives productivity with diagnostics, monitoring, and simplified access to powerful operations through the integrated touchscreen and browser interface
- Inert Flow Path provides improved performance for sensitive analytes at low levels, extending the range of quantitation and detection
- Simplify method development, from instrument settings to data analysis and reporting, with MassHunter Software